Dose finding study to determine the safety and tolerability of sotatercept (ACE-011) in adults with beta-thalassemia (β-thalassemia)

Update Il y a 4 ans
Reference: EUCTR2011-005659-15

Woman and Man

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Extract

To determine a safe, tolerable and effective dose of sotatercept in adult subjects with RBC transfusion-dependent beta-thalassemia major (including all subtypes)and β thalassemia intermedia, as well as non-transfusion dependent β-thalassemia intermedia.


Inclusion criteria

  • Subjects with red blood cell (RBC) transfusion dependent β-thalassemia major and β thalassemia intermedia, as well as non-transfusion dependent β-thalassemia intermedia will take part in this study