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A double-blind, randomized, multi-center active-controlled, parallel-group study comparing the combination of valsartan 320 mg plus hydrochlorothiazide 12.5 mg and valsartan 320 mg plus hydrochloroth...

Mise à jour : Il y a 4 ans
Référence : EUCTR2004-001197-10

A double-blind, randomized, multi-center active-controlled, parallel-group study comparing the combination of valsartan 320 mg plus hydrochlorothiazide 12.5 mg and valsartan 320 mg plus hydrochlorothiazide 25 mg to valsartan 320 mg in mild to moderate hypertensive patients not adequately controlled with valsartan 320 mg

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Extrait

To demonstrate the blood pressure reduction effect of valsartan/HCTZ 320/25 mg o.d. or 320/12.5 mg o.d. in patients with mild to moderate hypertension not adequately controlled with valsartan 320 mg monotherapy o.d. (MSDBP ≥90 mmHg and 110 mmHg at Visit 3) by testing the hypothesis that either valsartan/HCTZ 320/25 mg o.d. or valsartan/HCTZ 320/12.5 mg o.d. produces superior reduction in the mean sitting diastolic blood pressure (MSDPB) from baseline compared to valsartan 320 mg o.d alone

Critère d'inclusion

  • Mild to moderate hypertension

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