Extract

To evaulate the effect of K ATP channel blockade with glibenclamide on the symptomatic and counterregulatory hormonal responses to experimental hypoglycaemia.

Inclusion criteria

• We are testing the hypothesis that closing the K ATP channels using sulphonylureas (glibenclamide) during experimental insulin induced hypoglycaemia can help retain cerebral function and help enhance symptoms of hypoglycaemia in those with type 1 diabetes and hypoglycaemia unawareness

Links

• ictrp
• euctr