A pilot randomised controlled trial of occupational therapy to optimise recovery for patients undergoing primary total hip replacement for osteoarthritis Not provided at time of registration

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A multicentre phase II feasibility study of accelerated chemotherapy - sequential epirubicin followed by intravenous cyclophosphamide, methotrexate and fluorouracil - using pegfilgrastim for women with early stage breast cancer Not provided at time of registration

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BASIL-2: Bypass v Angioplasty in Severe Ischaemia of the Leg - 2 Background and study aims One in every 1000-2000 people in the UK will be diagnosed with advanced cases of Severe Limb Ischemia (SLI) yearly. As a result of a combination of smoking, diabetes, high bl...

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Lighten Up weight maintenance study Background and study aims There are a range of programmes that help people to lose weight, however most people tend to put weight back on. We need to find simple strategies that we can give to the pub...

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Which Healthy Heart Diet for people living with HIV? Background and study aims Successful treatment for HIV has lead to an ageing HIV-positive population with heart disease as the most common cause of death. The underlying cause of the increased risk of...

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A study of 177 Lutetium Dotatate in Children with Primary Refractory or Relapsed High-Risk Neuroblastoma http://www.cancerresearchuk.org/cancer-help/trials/a-trial-looking-177-lutetium-dotatate-neuroblastoma-children-young-people-ludo ?

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A study to determine the maximum tolerated dose and activity of the combination of Romidepsin and Carfilzomib in relapsed or refractory peripheral T-cell lymphoma http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-romidepsin-and-carfilzomib-for-people-with-peripheral-t-cell-lymphoma-that-has

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Safety, compliance with and activity of Bezafibrate and medroxyProgesterone acetate (BaP) as non-toxic therapy against myeloid and lymphoid cancers http://cancerhelp.cancerresearchuk.org/trials/trial-looking-new-combination-drugs-some-types-leukaemia-lymphoma

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Weigh 2 Go: The efficacy of water preloading before main meals as a strategy for weight loss in obese primary care patients Background and study aims There has been a dramatic increase in the number of people who are overweight/obese. Given this high rate of obesity there is a need to investigate the effectiveness of simpl...

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Increasing physical exercise to preserve beta cell function in adult patients with type 1 diabetes mellitus (T1DM) Not provided at time of registration

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