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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche par promoteur : GlaxoSmithKline Research & Development Limited
Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
Efficacy study to evaluate fluticasone furoate /vilanterol Inhalation Powder delivered once daily via the Dry Powder Inhaler Ellipta™ compared with usual ICS/LABA maintenance therapy delivered by Dry Powder Inhaler in subjects with Persistent Asthma
• The primary objective of the study is to compare the efficacy of FF/VI 92mcg/ 22mcg or FF/VI 184mcg/22mcg with usual fixed combinations ICS/LABA for asthma maintenance therapy at Week 12 (Visit 4).
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unknown
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
A 19-week, randomized, double-blind, placebo-controlled, three-period, cross-over pilot study comparing the effect of salmeterol/fluticasone propionate 50/100mcg BID, fluticasone propionate 100mcg BID and placebo on peripheral blood eosinophils and serum IL-5 in response to allergen challenge in asthma subjects
To investigate whether regular treatment with salmeterol in combination with fluticasone propionate (FP) has an effect on blood markers of airway inflammation compared with FP alone or placebo in resp...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
An open label, repeat dose, dose escalation study conducted in RLS patients to characterize pharmacokinetics and food effect of ropinirole controlled release for RLS
• To determine the effect of food on absorption of ropinirole CR-RLS at 6mg (highest tablet strength) • To demonstrate the dose proportionality for ropinirole CR-RLS over the dose range 1-6mg • To det...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
A two-centre, randomised, double-blind, double-dummy, placebo-controlled, 3-period cross-over study to evaluate the effect of treatment with repeat doses of GW274150 on the allergen-induced late asthmatic response in subjects with mild asthma
To evaluate the effect of treatment with repeat oral doses of GW274150 for 14 days on the late asthmatic response (LAR) to inhaled allergen in mild asthmatic subjects compared with placebo
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unknown
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
A Phase II Trial of Pazopanib, a Pan Vascular Endothelial Growth Factor Receptor (VEGFR) Inhibitor, in Relapsed or Refractory Small Cell Lung Cancer (SCLC)
To assess the activity of monotherapy pazopanib in terms of the progression-free rate in subjects with relapsed or refractory SCLC, all of whom have received one prior regimen of systemic chemotherapy...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
A randomized, single-blind, placebo-controlled, parallel-group study evaluating the anti-inflammatory activity of GSK315234 in synovial biopsy tissue obtained from subjects with rheumatoid arthritis
1. To assess the change in inflammatory biomarkers in the synovial tissue of subjects with rheumatoid arthritis (RA) on a background of methotrexate after administration of a single, intravenous dose ...
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unknown
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
A 28-day, Randomised, Double-Blind, Active Comparator, Controlled Study to Assess the Effects of Rosiglitazone, Inhaled Corticosteroid, Theophylline and Theophylline Plus Inhaled Corticosteroid on Inflammation and Pulmonary function in Asthmatic Smokers
Comparison of pre-bronchodilator (FEV1) at 28 days between rosiglitazone and Low Dose Inhaled Corticosteroid (LD ICS) treatment groups
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
A 52 week Randomised, Double-blind, Placebo-controlled Study to Investigate the Efficacy and Safety of GSK1605786A in the Maintenance of Remission in Subjects with Crohn's Disease Un estudio de 52 semanas aleatorizado, doble ciego, controlado con placebo para investigar la eficacia y la seguridad de GSK1605786A en el mantenimiento de la remisión en sujetos con Enfermedad de Crohn
- To assess the efficacy of GSK1605786A compared with placebo in maintaining clinical remission in subjects with Crohn's disease over 52 weeks. - Evaluar la eficacia de GSK1605786A en comparació...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
A randomised, single-dose, dose ascending, double-blind, placebo controlled, four-way, incomplete block crossover study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of inhaled doses of GW642444M with magnesium stearate in COPD patients
To evaluate the safety and tolerability of single doses of GW642444M with magnesium stearate (25, 50 and 100 mcg) in COPD patients
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Limited
MAJ Il y a 5 ans
Study PMA112509, a Phase I/II Study of Eltrombopag in Thrombocytopenic Subjects with Advanced Myelodysplastic Syndrome (MDS) or secondary Acute Myeloid Leukemia after MDS (sAML/MDS)
To evaluate the safety and tolerability of eltrombopag when administered to subjects with advanced MDS, sAML/MDS or de novo AML with 10-50% bone marrow blasts.
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unknown
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