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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche par promoteur : NOVARTIS
Femme et Homme Max 99 ans
NOVARTIS FARMA
MAJ Il y a 4 ans
A randomized, double-blind, placebo-controlled, multicenter phase III study of RAD001 adjuvant therapy in poor risk patients with Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 versus matching placebo after patients have achieved complete response with first-line rituximabchemotherapy
To compare disease-free survival (DFS) in poor risk patients with DLBCL after achieving CR following first-line R-CHOP who receive RAD001 versus patients who receive matching placebo.
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
NOVARTIS FARMA
MAJ Il y a 4 ans
Phase I study to examine the effect of deferasirox on renal hemodynamics in β-thalassemia patients with transfusional iron overload
To estimate the effects of deferasirox on changes from baseline in GFR and RPF using 51Cr-EDTA and 123I-Hippuran (I-hip) respectively and the corresponding filtration fraction (FF) in deferasirox na...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
NOVARTIS
MAJ Il y a 4 ans
Pharmacokinetic Study of LAF237 and Its Metabolites in Mild Renal Impaired Patients
This study will evaluate the pharmacokinetics of vildagliptin (LAF237) and its metabolites in patients with mild renal impairment compared to their sex, age and weigh based healthy volunte...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
NOVARTIS FARMA
MAJ Il y a 4 ans
A study to evaluate the effects of fingolimod teatment in patients with acute demyelinating optic neuritis
To assess if fingolimod will reduce the mean retinal nerve fiber layer (RNFL) thinning (measured as the OCT-determined difference between the RNFLT of the affected eye after 18 weeks of treatment and ...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
NOVARTIS FARMA
MAJ Il y a 4 ans
Once-a-day regimen or Steroid withdrawal in de novo kidney transplant recipients treated with everolimus, cyclosporin and steroids: a 12-month, prospective, randomized, multicenter, open-label study. The EVIDENCE study (EVerol/mus once-a-Day rEgimen with Neoral versus Corticosteroid Elimination)
The primary objective of the study is to demonstrate, in renal transplant patients receiving everolimus and cyclosporin, the non-inferiority of one of the two following regimens: once-a-day regimen (G...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
NOVARTIS FARMA
MAJ Il y a 4 ans
A long term extension to a randomised, double-blind, placebo-controlled, stratified, paralle-group, multicenter, dose-ranging study evaluating four oral doses of TCH346 1.0, 2.5, 7.5 and 15 mg administered once daily in patients with Amyotrophic Lateral Sclerosis
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
NOVARTIS FARMA
MAJ Il y a 4 ans
Safety and Efficacy of Secukinumab Compared to Etanercept in Subjects with Moderate to Severe, Chronic Plaque-Type Psoriasis Sicurezza ed efficacia di Secukinumab in confronto a Etarnecerpt in soggetti con psoriasi cronica a placche da moderata a severa
Efficacy of secukinumab compared to placebo in subjects with moderate to severe chronic plaque-type psoriasis over 12 weeks based on PASI and IGA Dimostrare la superiorità di secukinumab rispe...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
NOVARTIS FARMA
MAJ Il y a 4 ans
A multi-center, double-blind, placebo-controlled, randomized study to compare the effect of a subcutaneous canakinumab administration to placebo in patients with Impaired Glucose Tolerance or patients with Type 2 Diabetes treated with differing baseline diabetes therapies
The primary objective is to evaluate canakinumab effects on change from baseline of meal challenge derived insulin secretion rate relative to glucose 0-2 hours (Φd), at 4 weeks, on the following...
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Femme et Homme Max 99 ans
NOVARTIS FARMA
MAJ Il y a 4 ans
A Phase II study of BKM120 in patients with relapsed and refractory diffuse large B-cell lymphoma, mantle cell lymphoma and follicular lymphoma Studio di Fase II con BKM120 in pazienti con linfoma B diffuso a grandi cellule, linfoma mantellare e linfoma follicolare, recidivanti e refrattari
To determine the efficacy of BKM120 in patients with relapsed/refractory Non-Hodgkin Lymphoma in the three different histological subgroups (cohorts) Determinare l’efficacia di BKM120 in pazien...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
NOVARTIS FARMA
MAJ Il y a 4 ans
An open-label, multi-center study to evaluate the efficacy of nilotinib in adult patients with gastrointestinal stromal tumors resistant to imatinib and sunitinib
To evaluate the preliminary efficacy of nilotinib in pretreated patients with unresectable or metastatic gastrointestinal stromal tumors. Efficacy is defined as stable disease (SD), partial response (...
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