A Phase II Randomized, Placebo-Controlled Study to Evaluate the Safety and Efficacy of MK-7009 Administered Concomitantly With Pegylated-Interferon and Ribavirin for 28 Days in Treatment-Naïve Patients With Chronic Hepatitis C Infection To evaluate the activity, as measured by the proportion of patients achieving RVR (undetectable viral load at Week 4), and the safety and tolerability, as assessed by review of the accumulated safety ...

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A Phase IIa, Multicenter, Double-Blind, Randomized, Active Comparator-Controlled Clinical Trial to Study the Efficacy and Safety of MK-0893 in Combination With Sitagliptin or in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (1) To assess the effect of treatment with MK-0893 in combination with sitagliptin or metformin compared with sitagliptin in combination with metformin on 24-hour weighted mean glucose (WMG) after 4 w...

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Multicenter, open, pragmatic, randomized trial comparing the efficacy of 3 different lifestyle interventions after addition of sitagliptin to patients with type 2 diabetes mellitus who have inadequate glycemic control on metformin therapy After addition of Sitagliptin (JANUVIA®) to outpatients with T2DM who have inadequate glycemic control on metformin therapy - To compare the efficacy of three strategies of lifestyle changes associa...

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A Phase III, Double-Blind, Randomized, Placebo-Controlled, Multicenter Clinical Trial to Study the Safety, Tolerability, Efficacy, and Immunogenicity of V212/Heat-Treated Varicella-Zoster Virus (VZV) Vaccine in Recipients of Autologous Hematopoietic Cell Tranplants (HCTs) To assess the safety and tolerability of the heat-treated varicella-zoster vaccine (VZV) vaccine in recipients of autologous hematopoietic cell transplant (HCT). To assess the impact of the heat-treat...

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A phase III, Multicenter, Randomized, Placebo-Controlled Clinical Trial to Study the Safety and Efficacy of Oral MK-0974 in the Acute Treatment of Migraine with or Without Aura - To evaluate the efficacy of MK-0974 (300 mg and 150 mg) compared to placebo in the treatment of acute migraine as measured using pain freedom, pain relief, freedom from photophobia, freedom from pho...

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A Randomized, Double-Blind, Parallel-Group Study Conducted Under In-House Blinding Conditions to Determine the Efficacy and Tolerability of Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting Associated With Moderately Emetogenic Chemotherapy (Study #2) E.2.1 Main objective: 1. To demonstrate that the aprepitant regimen is superior to the control regimen with respect to the proportion of patient with no vomiting in the 120 hours following initiation...

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A Multicenter, Double-Blind, Randomized, Active-Controlled Study to Evaluate the Safety and Antiretroviral Activity of MK- 0518 Versus Efavirenz in Treatment Naïve HIV-Infected Patients, Each in Combination With TRUVADA™ 1.To evaluate the antiretroviral activity of MK-0518 400 mg b.i.d. compared with efavirenz 600 mg q.h.s., each in combination therapy with TRUVADA™, as measured by proportion of patients achieving HI...

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