Skin bacteria as a source of surgical infections: molecular epidemiology and prevention of wound contaimination The rise in antibiotic resistance, typified by MRSA, will inevitably result in an increase in life threatening wound infections after surgery. It is therefore proposed to pre-empt such a scenario by a...

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Testing a new approach to supporting people with bronchiectasis to take prescribed inhaled antibiotics Background and study aims Bronchiectasis is a lung condition in which the airways become permanently damaged. People who have bronchiectasis can have many different chest symptoms, commonly produce a ...

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Right from the start: Improving outcomes for children born to mothers in difficult circumstances Background and study aims Pregnancy is an important time for both mothers and their babies. For most people, it is a very positive time, when mothers-to-be can look forward to the arrival of a new chi...

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Text messaging as a way of helping overweight and obese women manage their weight after having a baby - The SMS study Background and study aims Many women are overweight or obese from the start of pregnancy and this puts the mother’s and baby’s health at risk. If a woman is overweight or obese in pregnancy she is at ...

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Pharmacokinetics of ketamine in infants To define the pharmacokinetic parameters of ketamine and its metabolites in infants and to determine the factors which lead to inter- and intra-patient variability

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Comparison of skin disinfection procedures before surgery to determine if surgical wound contamination by skin bacteria can be reduced Background and study aims An earlier study of spinal surgery, which we carried out at Queen’s University Belfast (UK) and Musgrave Park Hospital Belfast (UK), showed that nearly 30% of surgery wounds ...

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Evaluation of Team Alphie, a computerised literacy programme for children with literacy problems A plain English summary can be accessed on the Education Endowment Foundation website: http://educationendowmentfoundation.org.uk/projects/team-alphie /

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Evaluation of Quest Background and study aims Quest has evolved out of a project called Reading Edge, a computerised reading programme (intervention) that has been used in the United States. It is designed to help strugg...

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Testing of a new community pharmacy service to help older patients who live in their own homes and who are prescribed several medicines Background and study aims Older patients (aged 65 years or older) often have to take many medicines to treat several long-term medical conditions. This can include taking medicines in a range of diffe...

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An investigation into the modulation of obesity associated monocyte/macrophage function, vascular inflammation and insulin resistance by PPAR agonist treatment The proposed study will investigate early indicators of cardiovascular disease and diabetes in healthy, obese men without a family history of diabetes and whether these are changed by treatment with t...

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