Phase I/II trial for vaccine therapy with hTERT-, survivin- and tumor cell derived mRNA + ex vivo T cell expansion and reinfusion in patients with metastatic malignant melanoma Safety and toxicity of vaccination with DCs transfected with h-TERT mRNA, survivin mRNA and autologous tumor cell mRNA, lymphodepletion treatment and T cell expansion and reinfusion in patients with m...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

Kidney Cancer Integrated Therapy (KIT) - Personalized integrated therapy for patients with advanced kidney cancer The proposed interdisciplinary translational project will assist in the decision-making process for individualizing patient treatment. With our integrated approach we want to assess the feasibility of...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

Cabazitaxel mot cisplatin resistent testikkelkreft To evaluate the efficacy of cabazitaxel as monotherapy for the treatment of germ cell cancer. Efficacy is defined objective responses according to RECIST 1.1

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

A study investigating the use of additional chemotherapy for the improvement of efficacy, and the selection of breast cancer patients for such treatment in two paitent cohorts: Before surgery in curable patients and at time of metastatic disease The primary objective of the study is to determine the molecular (DNA, RNA, protein and metabolic) changes in the tumors with reference to the obtained response in the different treatment arms. The ...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

Treatment of delirium with clonidine The purpose of this randomised, controlled, parallel group pilot trial is to explore superiority of clonidine vs placebo in decreasing delirium symptoms (measured by MDAS scores) in patients diagnosed...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

Prevention of bladder dysfunction in acute spinal cord injury with Onabotulinumtoxin A To investigate if intravesical injection of Botox can prevent the development of bladder dysfunction after spinal cord injury

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

Dexmedetomidine versus midazolam til sedasjon av pediatriske intensivpasienter ved Oslo Universitetssykehus The main objective of the study is to elucidate whether sedation with dexmedetomidine will result in shorter time from decision of awakening until extubation than the traditional sedation with midazol...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

Antibiotic treatment in patients with chronic low back pain and bone edema on MRI adjacent to a previously herniated disc or adjacent to a degenerated disc: a double-blind study where patients at random are offered antibiotics or placebo tablets without knowing which tablets they are given To re-examine the finding that antibiotic treatment can cure patients with chronic low back pain, earlier disc herniation, and Modic changes. We will evaluate the effect of antibiotic treatment ver...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

Pain after operations for radius fractures To find out if single doses of dexamethasone and etoricoxib will reduce pain after radius fracture operation.

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

Patterns of loco-regional recurrence after conformal and intensity-modulated radiotherapy for head and neck cancer Background and study aims Head and neck cancer is a relatively uncommon type of cancer. Postoperative radiotherapy involves using doses of radiation to kill any cancer cells remaining after surgery t...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune