ACT against burnout (ACT gegen burnout) Background and study aims Burnout has been observed globally and is associated with numerous negative consequences ranging from depression, anxiety, low levels of self-esteem and well-being to decreas...

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Assessing the additional neoplasia yield of EndoRings™ in a colorectal cancer (CRC) screening setting Background and study aims Bowel (or colorectal) cancer is one of the most common types of cancer. If a person is suspected to have colorectal cancer, they may undergo a colonoscopy, an examination of...

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Preemptive analgesia with bupivacaine in mastectomy Not provided at time of registration

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Electrochemotherapy in basal cell carcinoma Background and study aims Basal cell carcinoma (BCC) is one of the most common types of skin cancer. It is usually caused by sun exposure and causes lumps, moles, lesions or patches of discoloured ski...

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Assessment of strangulated content of inguinal hernia spontaneously reduced during induction to anaesthesia through internal inguinal ring laparoscopy Not provided at time of registration

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Comparing stapled hemorrhoidopexy vs. open and closed hemorrhoidectomy Background and study aims Hemorrhoids, or piles, are swellings containing enlarged blood vessels found inside or around the anus and rectum. Most piles are mild and do not cause any problems, but symp...

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Pilot randomised controlled trial to assess the use of food diaries and pedometers on the glycaemic control and weight in people with type 2 diabetes requiring insulin that are obese Not provided at time of registration

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Can transthoracic echocardiography predict fluid responsiveness in shock after a mini-fluid challenge? Lay summary under review 2

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The CAPNO trial: a randomized controlled trial of two different methods of carbon dioxide detection in preterm infants in the delivery room Background and study aims The adaptation that all infants are required to make upon entering life outside of the womb is complex. Many physiological changes have to take place for the newborn to surv...

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The use of perianal methylene blue injection on post-haemorrhoidectomy pain Background and study aims Haemorrhoids, also known as piles, are swellings containing enlarged blood vessels that are found inside or around the bottom (the rectum and anus). Surgery to remove haemor...

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