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Kusajili – Centralise les essais cliniques mondiaux
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de votre recherche par promoteur : pubmed
pubmed
MAJ Il y a 5 ans
NCT0102455
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pubmed
MAJ Il y a 5 ans
Population pharmacokinetics of rifampicin and 25-deacetyl-rifampicin in healthy Asian adults.
Rifampicin is a first-line anti-TB drug. The objectives of this analysis were to evaluate the population pharmacokinetics of rifampicin and its partly active metabolite, 25-deacetyl-rifampicin, with a...
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pubmed
MAJ Il y a 5 ans
Increase in insulin action and fat oxidation after treatment with CL 316,243, a highly selective beta3-adrenoceptor agonist in humans.
Stimulation of beta3-adrenoceptors by selective agonists improves insulin action and stimulates energy metabolism in various rodent models of obesity and type 2 diabetes. Whether selective beta3-adren...
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pubmed
MAJ Il y a 5 ans
Tigecycline does not prolong corrected QT intervals in healthy subjects.
We evaluated the effect of tigecycline (50-mg and 200-mg doses) on corrected QT (QTc) intervals and assessed safety and tolerability in a randomized, placebo-controlled, four-period crossover study of...
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pubmed
MAJ Il y a 5 ans
Exercise within lower body negative pressure partially counteracts lumbar spine deconditioning associated with 28-day bed rest.
Astronauts experience spine deconditioning during exposure to microgravity due to the lack of axial loads on the spine. Treadmill exercise in a lower body negative pressure (LBNP) chamber provides axi...
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pubmed
MAJ Il y a 5 ans
Effect of vitamin E therapy on blood coagulation tests in newborn infants.
A double-blind randomized trial of vitamin E therapy was conducted in premature infants whose birth weight was less than 1,500 gm. Treated infants received 25 mg of vitamin E daily by mouth for the fi...
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pubmed
MAJ Il y a 5 ans
Diagnostic accuracy of probe-based confocal laser endomicroscopy in detecting residual colorectal neoplasia after EMR: a prospective study.
Residual neoplasia after EMR of colorectal lesions is common. There is a critical need for imaging methods to accurately diagnose residual disease and to guide retreatment in real time. The aim was to...
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pubmed
MAJ Il y a 5 ans
Why do patients seek an alternative channel? The effects of unmet needs on patients' health-related Internet use.
Breast cancer is the most common form of cancer found among women in the United States. During the course of the illness, women diagnosed with breast cancer need information and support to cope with t...
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pubmed
MAJ Il y a 5 ans
Gentamicin and gentamicin C1 in the treatment of complicated urinary tract infections: comparative study of efficacy, tolerance, and pharmacokinetics.
The clinical efficacy, patient tolerance, and pharmacokinetics of gentamicin and the single component gentamicin C(1) were studied after single and multiple doses in elderly male patients. Patient tol...
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pubmed
MAJ Il y a 5 ans
A randomized controlled trial of brief coparenting and relationship interventions during the transition to parenthood.
The transition to parenthood has been repeatedly identified as a stressful period, with couples reporting difficulties in domains of individual, coparenting, and relationship functioning. Moreover, th...
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