Mobile
Search
Advanced search
Multi-criteria search
Who are we ?
Log in
Sign up
Français
English
Kusajili – Clinical trials directory
Result
of your search per sponsor: Hoffmann-La Roche
Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
A multi-center, double-blind, randomized, placebo-controlled dose-ranging phase 2 study to investigate efficacy, safety, tolerability and pharmacokinetics of RO4389620 in patients with type 2 diabetes mellitus treated with a stable dose of metformin
To determine the BID dose(s) of RO4389620 administered in combination with metformin, which when compared to placebo (metformin monotherapy) are efficacious, safe and tolerable in improving glycemic c...
Country
None
organs
None
Specialty
None
Closed trial
More information
Woman and Man
Between 18 years
and 99 years
Hoffmann-La Roche
Update Il y a 4 ans
HOFFMANN LA ROCHE MO21926 : Essai de phase 2 évaluant l’efficacité et la tolérance de l’association bévacizumab, trastuzumab et capécitabine, en traitement de première ligne, chez des patients ayant un cancer du sein HER2+ en rechute locale ou métastatique. [Informations issues du site clinicaltrials.gov et traduites par l'INCa] [essai clos aux inclusions]
A single arm open-label, phase II study of bevacizumab in combination with trastuzumab and capecitabine as first-line treatment of patients with HER2-positive locally recurrent or metastatic breast ca...
Country
France
organs
Sein
Specialty
Thérapies Ciblées
,
Chimiothérapie
Essai clos aux inclusions
More information
Woman
Between 18 years
and 99 years
Hoffmann-La Roche
Update Il y a 4 ans
Étude MORPHEUS TNBC : étude de phase 1b-2 randomisée évaluant l’efficacité et la sécurité de l’atézolizumab, du cobimétinib, de l’ipatasertib, du bévacizumab et du SGN-LIV1A en traitement combiné chez des patientes ayant un cancer du sein triple négatif après progression pendant ou après un traitement de première ligne par chimiothérapie.
Le cancer du sein triple négatif représente 15 à 20 % des cas de cancers du sein nouvellement diagnostiqués. Pour ce type de cancer, il n’existe pas de thérapies ciblées approuvées et la chimiothérapi...
Country
France
organs
Sein
Specialty
Immunothérapie - Vaccinothérapie
,
Chimiothérapie
,
Thérapies Ciblées
Essai ouvert aux inclusions
More information
Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
International study evaluating safety of Obinutuzumab alone or in combination with chemotherapy in patients with Chronic Lymphocytic Leukemia
• To evaluate the safety and tolerability of obinutuzumab alone or in combination with chemotherapy
Country
None
organs
None
Specialty
None
unknown
More information
Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
A study of MDPL3280A in patients with advanced bladder cancer
Evaluated the efficacy of MPDL3280A in patients with locally advanced or metastatic urothelial bladder cancer as measured by independent review facility assessed ORR using RECIST v1.1 and investigator...
Country
None
organs
None
Specialty
None
unknown
More information
Woman Max 99 years
F. Hoffmann-La Roche Limited
Update Il y a 4 ans
A randomised, double blind, placebo-controlled, multi-centre study to evaluate the efficacy and safety of bevacizumab in combination with docetaxel compared with docetaxel plus placebo, as first line treatment for patients with HER2 negative metastatic breast cancer
To compare Progression Free Survival (PFS) in patients randomised to • bevacizumab 7.5 mg/kg and docetaxel 100 mg/m[2] q3wk versus docetaxel 100 mg/m[2] and bevacizumab placebo q3wk or • bevacizumab ...
Country
None
organs
None
Specialty
None
unknown
More information
Woman and Man
Between 18 years
and 99 years
Hoffmann-La Roche
Update Il y a 4 ans
Etude WO29519 : étude randomisée, en double aveugle, de phase 3, comparant l’association de la cytarabine avec de l’idasanutlin (antagoniste du MDM2) ou avec un placebo chez des patients ayant une leucémie aiguë myéloïde (LAM) réfractaire ou en rechute.
La leucémie aigüe myéloïde (LAM) est un cancer qui prend naissance dans les cellules souches du sang. Ces cellules initialement normales se développent anormalement pour devenir des cellules immatures...
Country
France
organs
Leucémies aiguës
Specialty
Chimiothérapie
,
Thérapies Ciblées
Essai ouvert aux inclusions
More information
Woman and Man
Between 18 years
and 99 years
Hoffmann-La Roche
Update Il y a 4 ans
HOFFMANN LA ROCHE MO22223 : Essai de phase 3 randomisé comparant l’efficacité du bévacizumab associé ou non à de la capécitabine, en traitement de maintenance, chez des patients ayant un cancer du sein métastatique HER2-. [Informations issues du site clinicaltrials.gov et traduites par l'INCa] [essai clos aux inclusions]
A randomized study of the effect of maintenance therapy with bevacizumab + capecitabine versus bevacizumab alone on progression-free survival in patients with HER2-negative metastatic breast cancer th...
Country
France
organs
Sein
Specialty
Thérapies Ciblées
Essai clos aux inclusions
More information
Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
A Phase II, prospective, randomized, double-blind, active-controlled, parallel group, multi-center 'proof of concept' trial in adult patients with community-acquired pneumonia requiring hospitalization without evidence of Legionella
To compare the safety, tolerance and efficacy of parenteral RO4908463 to ceftriaxone in patients with community-acquired pneumonia requiring hospitalization without evidence of Legionella.
Country
None
organs
None
Specialty
None
Closed trial
More information
Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
A Study to Compare the Efficacy and Safety of Obinutuzumab + GDC-0199 versus Obinutuzumab + Chlorambucil in Patients with Chronic Lymphocytic Leukemia
To determine efficacy by investigator-assessed PFS of a combined regimen of obinutuzumab and Venetoclax compared with GClb in previously untreated patients with CLL who have coexisting medical conditi...
Country
None
organs
None
Specialty
None
unknown
More information
Previous
10
11
12
13
14
15
16
17
18
19
Next