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A 90-week, multi-center, randomized, double-blind, placebo-controlled study in patients with mild Alzheimer’s Disease (AD) to investigate the safety, tolerability and Abeta-specific antibody response ...

Update Il y a 4 ans
Reference: EUCTR2009-012394-35

A 90-week, multi-center, randomized, double-blind, placebo-controlled study in patients with mild Alzheimer’s Disease (AD) to investigate the safety, tolerability and Abeta-specific antibody response following repeated i.m. injections of adjuvanted CAD106

Woman and Man

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Extract

• To assess the safety and tolerability of up to 7 repeated injections of CAD106 with or without adjuvant (Alum or MF59) in patients with mild Alzheimer’s Disease (AD) over 90 weeks. • To compare the immunogenicity of CAD106 with Alum or MF59 in patients with mild Alzheimer’s Disease (AD) as measured by the titers of Aβ-specific IgG in serum across regimens and in reference to non-adjuvanted CAD106.

Inclusion criteria

  • Alzheimer's disease

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