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A Crossover Study to Evaluate Relative Bioavailability of Simeprevir Age-appropriate Oral Formulation Candidates Compared with 150-milligram (mg) Oral Capsule in Healthy Adult Participants

Update Il y a 4 ans
Reference: EUCTR2014-005448-17

Woman and Man

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Extract

- To compare the rate and extent of absorption of SMV following administration of a single dose of two different oral formulation candidates and following administration of a single dose of the 150-mg oral capsule, after a standardized breakfast in healthy adult subjects. - To compare the rate and extent of absorption of SMV following administration of a single dose of a selected oral formulation candidate in the fed (standardized breakfast) and fasted state in healthy adult subjects. - To compare the rate and extent of absorption of SMV following administration of a single dose of a selected oral formulation candidate after intake with water and after intake with yoghurt or apple juice, after a standardized breakfast in healthy adult subjects.

Inclusion criteria

  • Chronic Hepatitus C Virus (HCV) Infection

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