Extract

To determine the maximum-tolerated dose (MTD) in terms of the incidence of dose-limiting toxicity (DLT) of panobinostat in combination with ara-C and mitoxantrone at a fixed dose in adult patients with relapsed or is primary refractory acute myeloid leukemia (AML).

Inclusion criteria

• refractory or relapsed acute myeloid leukemia

Links

• ictrp
• euctr