Treating the gut flora to improve heart failure The main objective of the study is to investigate the gut microbiota as a potential therapeutic target in HF: • By characterizing the composition of gut microbiota in HF patients compared to health...

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PHASE I/IIa STUDY OF VACCINE THERAPY IN PATIENTS WITH NON-SMALL CELL LUNG CANCER Immunological response to UV1 vaccine and assessment of safety and tolerability of UV1.

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Opioid induced hypersensitivity: possible to avoid by different withdrawal regimens? Comparing gradual reduction from remifentanil infusion to acute withdrawal with regards to opioid induced hyperalgesia.

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A phase II study of pembrolizumab in patients with malignant peripheral nerve sheath tumor (MPNST), not eligible for curative surgery Main Objective: To evaluate the percentage of patients with curatively unresectable MPNST who have achieved clinical response; complete response (CR), partial response (PR), or stable disease (SD) at ...

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Therapeutic effects of a cardiac hormone, named BNP, in patients with poorly controlled high levels of blood pressure To demonstrate safety and to determine most effective dose of subcutaneous nesiritide in patients with UHT.

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Clinical study with cancer vaccine combined with Anti-PD1 (Pembrolizumab) in malignant lymphoma The main objectives of the trial is to induce systemic immune responses against the lymphoma and correlated clinical responses, and additionally study feasibility and safety

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A national phase IV study with Ipilimumab for patients with advanced malignant melanoma •To estimate the incidence and severity of adverse reactions in adult patients treated with ipilimumab in the post-approval setting. •To describe the management of adverse reactions (eg, diarrhea, co...

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Expectations among musculoskeletal patients Background and study aims Patients’ expectations may be linked to their characteristics and the outcome of their treatment. However, few studies have investigated if or how physical medicine and rehab...

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The COPE LBP trial: Cognitive Patient Education for Low Back Pain Not provided at time of registration

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ADJUVANT CHEMOTHERAPY IN ELDERLY CRC– ACE Study The main objective is to investigate the tolerance of adjuvant chemotherapy, measured by functional decline, after surgery for colon cancer stage III in elderly patients.

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