Woman and Man
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Extract
Feasibility Trial Primary objective: This is a trial to determine whether it is possible to restore and maintain blood albumin levels to near normal in patients admitted to hospital with complications due to advanced liver disease. The patients will be given repeated doses of 100ml 20% Human Albumin Solution (HAS) straight into their veins. HAS will be prescribed according to the albumin levels in the blood measured by standard blood tests. Randomised Control Trial Primary objective: This is a trial to confirm whether increasing the blood albumin level to near normal in patients admitted to hospital with advanced liver disease using repeated dosing of HAS will reduce chances of the development of hospital-acquired infection, organ dysfunction and death for the treatment period. Patients will be allocated at random to receive either HAS or standard medical care to compare the two treatments.
Inclusion criteria
- Liver cirrhosis