Extrait

Background and study aims Chronic venous insufficiency is a medical condition where the veins cannot pump enough blood back to the heart. The disease mainly occurs in the legs and more commonly affects women. The symptoms of this disease include pain, swelling and redness of the legs. The main complications are ulcers and skin diseases. Treatment includes the wearing of special stockings which compress the legs. There are different types of stockings which exert different pressures on the legs. The aim of this study is to compare the effectiveness and tolerability of two types of stockings, one where the pressure increases from the ankle to the knee (progressive), and one where the pressure decreases from the ankle to the knee (degressive). Who can participate? Adult patients with moderate chronic venous insufficiency. What does the study involve? Participants are randomly allocated to wear one of the two types of stocking. What are the possible benefits and risks of participating? Should the new progressive type of stocking be more effective and/or better tolerated than the degressive stockings, patients in this group will have a better treatment. In the degressive group there will be no disadvantage since the patients will receive the usual treatment. In addition, as in any study the patients will be followed up more closely and the stockings will be given for free. There could be local discomfort such as constriction and skin irritation in both groups. Where is the study run from? Pierre Fabre Laboratories (France). When is the study starting and how long is it expected to run for? June 2007 to September 2008. Who is funding the study? Pierre Fabre Laboratories (France). Who is the main contact? Dr Serge Couzan

Critère d'inclusion

• Chronic venous desease (or insufficiency)

Liens

• ictrp
• isrctn