Extract

To evaluate the safety and efficacy profile of three different treatment regimens of INCB018424 administered to two groups of patients; those with polycythemia vera (PV) and those with essential thrombocythemia (ET). Patients in each group will be refractory to hydroxyurea or for whom hydroxyurea is contraindicated.

Inclusion criteria

• advanced polycythemia vera or essential thrombocythemia refractory to hydroxyurea

Links

• ictrp
• euctr