Woman and Man
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Extract
The study has hierarchical co-primary objectives to demonstrate that: • Firstly: dexmedetomidine is at least as effective as sedation with midazolam and daily sedation stops, in maintaining a target depth of sedation in ventilated patients in intensive care unit (ICU) • Secondly: use of dexmedetomidine, compared with sedation with midazolam and daily sedation stops, reduces the duration of mechanical ventilation in ventilated patients in ICU
Inclusion criteria
- Patients requiring mechanical ventilation and sedation in ICU