A PHASE III PLACEBO-CONTROLLED TRIAL OF CELECOXIB IN GENOTYPE POSITIVE SUBJECTS WITH FAMILIAL ADENOMATOUS POLYPOSIS

Mise à jour : Il y a 5 ans
Référence : EUCTR2006-002228-40

Femme et Homme

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Extrait

To compare the time from randomization to treatment failure over a five year period for subjects treated with celecoxib versus subjects treated with placebo, where treatment failure is defined as the earliest occurrence of one or more of the following: a. Appearance of ≥20 polyps (>2 mm in size) at any colonoscopy during the study; OR b. Diagnosis of colorectal malignancy.


Critère d'inclusion

  • GENOTYPE POSITIVE SUBJECTS WITH FAMILIAL ADENOMATOUS POLYPOSIS