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A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of JNJ-39588146 in Subjects with Heart Failure ...

Mise à jour : Il y a 4 ans
Référence : EUCTR2009-013929-42

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of JNJ-39588146 in Subjects with Heart Failure Uno studio randomizzato, in doppio cieco, controllato con placebo, a gruppi paralleli per studiare la sicurezza, la tollerabilita`, la farmacodinamica e la farmacocinetica di JNJ-39588146 in soggetti con insufficienza cardiaca

Femme et Homme

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Extrait

Assess the hemodynamic effects, the safety and the tolerability of JNJ-39588146 when administered by intravenous infusion to male subjects and female subjects of non-childbearing potential with New York Heart Association (NYHA) Class II-IV heart failure. Valutare gli effetti emodinamici, la sicurezza e la tollerabilita' di JNJ-39588146 somministrato tramite infusione endovenosa a soggetti di sesso maschile e femminile potenzialmente non fertili, affetti da insufficienza cardiaca di classe NYHA (New York Heart Association) II o IV.

Critère d'inclusion

  • Heart failure,scompenso cardiaco

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