Bile salt manipulation as a novel treatment for Crohn’s disease: a single centre open label pilot study of atorvastatin and colesevalam in patients with active ileal Crohn’s disease

Update Il y a 4 ans
Reference: EUCTR2009-010163-16

Woman and Man

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Extract

To investigate the clinical benefit - in terms of mucosal healing and symptomatic improvement - of treatment with a combination of statins and cholestyramine (to reduce bile acid concentration) in patients with mild to moderately active ileal Crohn’s disease.


Inclusion criteria

  • Active Crohn's disease affecting the ileum