Evaluation of Platelet Function After Statin Loading Dose in Patients Before Percutaneous Coronary Intervention

Mise à jour : Il y a 5 ans
Référence : NCT01526460

Femme et Homme

  • | Pays :
  • Italy
  • | Organes :
  • -
  • | Spécialités :
  • -

Extrait

The purpose of this study is to evaluate the effect of a loading dose of two different statins on platelet reactivity (atorvastatin, metabolized by CYP3A4, and rosuvastatin, which is rather independent of this enzyme)in patients at least 5 days in therapy with aspirin and clopidogrel (with or without an undergoing treatment with statins) undergoing PCI for coronary disease with chronic stable angina and/or evidence of inducible myocardial ischemia.


Critère d'inclusion

  • Platelet dysfunction

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