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A randomised, double-blind, placebo-controlled study to evaluate the transthoracic Doppler echocardiography method as a non-invasive method for coronary function measurements; ability to detect short-...

Mise à jour : Il y a 5 ans
Référence : EUCTR2008-002332-15

A randomised, double-blind, placebo-controlled study to evaluate the transthoracic Doppler echocardiography method as a non-invasive method for coronary function measurements; ability to detect short-term statin effects in patients with increased cardiovascular risk

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Extrait

· To evaluate the change after 1 month statin treatment in transthoracic Doppler echocardiography-coronary flow reserve (TTDE-CFR) peak velocity compared to baseline within the rosuvastatin 40 mg group · To evaluate the difference in treatment effects on CFR peak velocities after 1 month between the rosuvastatin group and the placebo group in favour of the rosuvastatin group

Critère d'inclusion

  • In this study the IMP, rosuvastatin, is used as a tool compound for creating favourable lipid-altering, anti-inflammatory or other pleiotropic effects which are believed to change coronary flow reserve (CFR)

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