Femme et Homme
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Extrait
To determine the safety and tolerability profile of multiple-dose, every 14-day, intravenous (iv) administration of XmAb5871 in patients with RA
Critère d'inclusion
- XmAb5871 is a humanized Fc engineered monoclonal antibody that binds to the human B cell restricted cell surface antigen CD19. It has already entered Phase 1 clinical development. The available evidence suggests that XmAb5871 is a potentially useful immunomodulatory antibody for therapy of B cell mediated human disease states such as rheumatoid arthritis