Mobile

Trial to study the pharmacokinetics and food effect of solid and liquid formulations of TMC435 versus the reference

Mise à jour : Il y a 4 ans
Référence : EUCTR2011-005808-14

Femme et Homme

  • | Pays :
    • -
  • | Organes :
    • -
  • | Spécialités :
    • -

Extrait

• To compare the rate and extent of absorption of TMC435 following administration of a single dose of 2 different liquid formulations to that following administration of a single dose of the Phase III 150 mg capsule, after a highfat breakfast in healthy adult subjects. • To compare the rate and extent of absorption of TMC435 following administration of a single dose of 2 different liquid formulations in the fed (high-fat) and fasted state in healthy adult subjects. • To compare the rate and extent of absorption of TMC435 following administration of a single dose of 2 different capsule concept formulations to that following administration of a single dose of the Phase III 150 mg capsule, after a high-fat breakfast in healthy adult subjects.

Critère d'inclusion

  • Hepatitis C Virus (HCV) genotype-1 infection

Liens