Extrait

Background and study aims Bowel polyps are small, benign (harmless) growths found on the inner lining of the colon (end part of the large intestine) or rectum. They are not usually cancerous, however if they are found they should be removed as some will eventually turn into cancer if left untreated. People who have been found to have bowel polyps need to undergo surveillance to monitor their growth. Current UK guidelines for the surveillance of people found to have bowel polyps classify people into those who are at low, intermediate or high risk of developing bowel cancer in the future. This guideline was developed in 2002 and now needs to be re-examined. People with intermediate risk bowel polyps are currently recommended to have 3-yearly surveillance colonoscopy (test to look inside the intestine with a camera on a flexible tube). This is likely a good option for some people in the intermediate risk group, but it may not be the best option for others. The aim of this study is to evaluate the effectiveness of the current surveillance guidelines. Who can participate? Men and women of any age who have bowel polyps who have had a colonoscopy What does the study involve? The study uses material from several high quality databases in hospitals or from bowel cancer screening initiatives to identify groups of patients with bowel polyps. Information from routine colonoscopies conducted to the current surveillance programme is collected and used to see if patient’s polyps worsen or turn into cancer at later visits. What are the possible benefits and risks of participating? There are no direct benefits or risks involved for those participating. Where is the study run from? Cancer Screening and Prevention Research Group (UK) When is the study starting and how long is it expected to run for? September 2006 to December 2017 Who is funding the study? Health Technology Assessment Programme (UK) Who is the main contact? 1. Ms Paula Kirby (public) [email protected] 2. Professor Wendy Atkin [email protected]

Critère d'inclusion

• Patients with intermediate-risk adenoma(s) (three or four small adenomas or one or two large adenomas)

Liens

• isrctn