Femme et Homme
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Extrait
Primary Doses • To assess the performance of alternative dosing regimens for primary immunization with Q-Pan H5N1 vaccine using an immunogenicity-fever index that considers: - immunogenicity by Hemagglutination Inhibition (HI) assay 21 days after the second priming dose. - fever scores after the first and second priming doses. - immunogenicity by Microneutralization (MN) assay 21 days after the second priming dose. - fever scores after the first and second priming doses. Booster Dose • To assess the performance of dosing regimens for booster immunization with Q-Pan H5N1 vaccine considering: - immune response (IR) by HI assay 7 days after a 12-month booster dose of Hemagglutinin (HA) Q-Pan H5N1 plain antigen. - immune response by MN assay 7 days after a 12-month booster dose of HA Q-Pan H5N1 plain antigen.
Critère d'inclusion
- Healthy volunteers (Active immunization against influenza A virus H5N1 subtype)