Extrait

Background and study aims Impacted mandibular third molar extraction (also known as wisdom teeth removal) is one of the most common operations in oral and maxillofacial (mouth and teeth) surgery. Wisdom teeth grow at the back of the mouth and are the last teeth that come up through the gums, usually when people are young adults. Due to a lack of space, wisdom teeth can come through the gums on an angle causing them to be impacted. This usually means they need to be removed surgically. The operation consists of a small cut into the gum, extracting (removing) the tooth and then stitching up the area where the tooth was. Usually, the wound heals within a week or two however patients can experience some pain and are at risk of developing dry socket (a dull ache in the gum or jaw and a bad smell or taste coming from the area the tooth was removed). In order to encourage healing, platelet rich fibrin (PRF) has been suggested to be used on the tooth removal area. PRF is collected from the patients’ blood and is then processed to separate out the platelets in order to be placed on the site where the tooth was removed. PRF is thought to help increase healing and reduce the possibility of complications. The aim of this study is to see how well PRF helps reduce edema (swelling) and pain after impacted mandibular third molars surgery. Who can participate? Adults aged 17-27 who require the removal of their impacted mandibular third molar. What does the study involve? Participants give a small sample of blood which is then processed in order to separate out the PRF. Participants then undergo the removal of their wisdom teeth in their lower jaw. Both of the lower wisdom teeth (right and left) are removed according to the standard level of care. However, the right side tooth removal area receives PRF (placed on the area with dental forceps (tool)) and the left side tooth removal area does not receive PRF. Both tooth removal areas are stitched up. Participants receive follow up for seven days after the procedure where they are tested for pain and edema. What are the possible benefits and risks of participating? Participants may benefit from a shorter recovery time. There are no notable risks with participating however participants may feel some discomfort when giving the blood sample. Where is the study run from? Ankara University Dentistry Faculty Oral and Maxillofacial Surgery Department (Turkey) When is the study starting and how long is it expected to run for? June 2011 to October 2013 Who is funding the study? Investigator initiated and funded Who is the main contact? Dr Mehmet Fatih Şentürk [email protected]

Critère d'inclusion

• Bilateral impacted third molars

Liens

• isrctn