Extrait

Background and study aims Major trauma accounts for a significant number of deaths worldwide, and is one of the most frequent causes of death in people under the age of 40. When a person sustains trauma (injury) to multiple parts of the body (multitrauma) they are at risk of their organs shutting down if their condition is not managed effectively in hospital. Multiple organ dysfunction syndrome (MODS), is a serious condition where two or more organ systems stop working properly. Being able to identify a patient’s risk of developing MODS following multitrauma would be very beneficial and help improve the patient’s chance of survival. The aim of this study is to find out whether completing a number of standard medical assessments of multitrauma patients can help to predict their chance of developing MODS. Who can participate? Adults who have suffered from trauma in multiple body regions. What does the study involve? Mutlitrauma patients who have been admitted to the Emergency Department of a participating hospital are assessed by the research team. This involves taking blood samples, physically examining the patients and assessing the extent of their trauma. These assessments are repeated every 24 hours until the patient is discharged from hospital in order to find out if there is a link between the results of these tests and the development of MODS. What are the possible benefits and risks of participating? Participants benefit from having the possibility of them developing MODS being identified sooner so they can be treated sooner. There are no notable risks involved with participating. Where is the study run from? 1. Department of surgery, Univeristy of Sam Ratulangi (Indonesia) 2. Department of surgery, University Diponegoro (Indonesia) 3. Departement of surgery, University Udayana (Indonesia) 4. Departement of surgery, University Hasanuddin (Indonesia) When is the study starting and how long is it expected to run for? September 2014 to December 2015 Who is funding the study? Investigator initiated and funded (Indonesia) Who is the main contact? Dr Leo Rendy [email protected]

Critère d'inclusion

• Multiple Organ Dysfunction Syndrome

Liens

• isrctn