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Extrait
The purpose of this study is to assess the effect of multiple doses of isavuconazole on the pharmacokinetics of a single dose of methotrexate. Safety and tolerability of isavuconazole will be assessed alone and in combination with methotrexate.
Critère d'inclusion
- Pharmacokinetics of Isavuconazole,Pharmacokinetics of Methotrexate,Pharmacokinetics of 7-hydroxymethotrexate,Healthy subjects