Controlled Human Exposure to Indoor Air, Dust and Ozone

Mise à jour : Il y a 4 ans
Référence : NCT02017782

Femme et Homme

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Extrait

The aim of the study is to provide information which may help to improve the quality of the life of persons exposed to indoor environments in Danish dwellings. The experiment will document if dust and ozone contribute to deterioration of indoor air quality and to the occurrence of symptoms and health effects. The study is aimed at testing the hypothesis that the presence of ozone potentiate the health and comfort effects of dust exposure in the indoor environment. Testing this hypothesis will be based on the following questions: Does house dust and ozone in concentrations frequently encountered in Danish dwellings cause unwanted health effects either by themselves or by interaction? If so, does the presence of ozone potentiate the expected irritative effects of dust? The challenge of these hypotheses will be made as a controlled experiment on humans in a climate chamber under controlled exposure conditions. This controlled human experiment should be able to substantiate the findings from the intervention studies. Furthermore, they ideally reflect something relevant to the general public and therefore should have maximum public appeal and application possibilities.


Critère d'inclusion

  • Subjective Discomfort,General Mucosal Irritation,Acute Changes in Respiratory Outcomes,Acute Changes in Cardiovascular Outcomes,Changes in Biomarkers

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