A PHASE I/II, OPEN LABEL STUDY OF SPC2996 IN COMBINATION WITH RITUXIMAB FOR THE TREATMENT OF RELAPSED FOLLICULAR OR LYMPHOPLASMACYTIC NON-HODGKIN’S LYMPHOMA

Update Il y a 4 ans
Reference: EUCTR2008-001353-17

Woman and Man

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Extract

Primary: 1. To determine the MTD of SPC2996 in combination with rituximab in patients with relapsed follicular or lymphoplasmacytic non-Hodgkin’s lymphoma 2. To determine the overall response rate (Complete Response [CR] + Partial Response [PR]) of the combination of SPC2996 and rituximab in the treatment of relapsed follicular or lymphoplasmacytic non- Hodgkin’s lymphoma 3. To determine the safety and tolerability of the combination of SPC2996 and rituximab in patients with relapsed follicular or lymphoplasmacytic non-Hodgkin’s lymphoma


Inclusion criteria

  • Follicular Lymphoma (FL); Lymphoplasmacytic (lymphoplasmacytoid) Lymphoma (LPL) / Waldenstrom’s macroglobulinemia (WM)