Extract

To compare the gastrointestinal (GI) tolerability of deferasirox administered before and after meals in patients with iron overload due to multiple blood transfusions, on established deferasirox therapy. The primary endpoint is the difference in mean individual Gastrointestinal Quality of Life Index (GIQLI)score change from baseline to end of study in the before-meals arm versus after-meals arm.

Inclusion criteria

• transfusional haemosiderosis

Links

• ictrp
• euctr