Tropomyosin receptor kinase antagonism in cylindromatosis Background and study aims This study aims to evaluate a new ointment to treat an inherited skin tumour condition called cylindromatosis. Patients from families with this condition carry an error in t...

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Targeting the Rheumatoid Arthritis Synovial Fibroblast via Cyclin Dependent Kinase Inhibition - an early phase trial (TRAFIC) Background and study aims Rheumatoid arthritis is a long-term condition causing pain, swelling and stiffness in the joints. The main aim of this study is to find out how much of the drug seliciclib ca...

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