A randomised, open study to assess the safety and efficacy of a new artesunate-mefloquine coformulation with an equivalent dose regimen of the individual drugs for the treatment of acute uncomplicated falciparum malaria (Thailand) Background and study aims Malaria is a serious tropical disease caused by a parasite spread by mosquitoes. Malaria has become increasingly difficult to treat over the last 50 years. The reason is tha...

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The Africa Quinine versus Artesunate in Severe Malaria Trial Background and study aims. This was the largest ever study in children hospitalized with severe malaria. It sought to determine whether a drug called artesunate was a better treatment than the usual ...

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A phase III, randomised, non-inferiority trial, to assess the efficacy and safety of dihydroartemisinin and piperaquine (DHA + PPQ, Artekin®) in comparison with artesunate and mefloquine (AS + MQ) in patients affected by acute, uncomplicated Plasmodium falciparum malaria Not provided at time of registration

• Pays India, Lao People's Democratic Republic, Thailand
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Levamisole hydrochloride as adjunctive therapy in falciparum malaria Not provided at time of registration

• Pays Thailand
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