European Intravitreal Avastin® Trial 1 To investigate functional vision outcomes of intravitreal Bevacizumab (Avastin®), a recombinant humanized anti-VEGF monoclonal antibody, administered as multiple intraocular injections in patients wit...

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Interdisciplinary Innovative model of care for people with Hand OsteoArthritis Background and study aims Hand osteoarthritis is one of the most common rheumatic diseases, concerning 60-70% of the population over 65 years. The small finger joints are affected in particular. This ...

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Anti-inflammatory and/or antinociceptive effects of botulinum toxin A in an experimental inflammatory human skin pain model: a randomised, double blinded, placebo controlled study The objectives of the present study are to demonstrate potential antiinflammatory, antihyperalgesic on the peripheral and/or central level effects of Botulinum toxin a (Dyport).

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Intrahospital first medical contact (iFMC) to electrocardiogram (ECG): how to improve intrahospital delays! Not provided at time of registration

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PET/MRI in patients with suspected prostate cancer PET/MRT bei Patienten mit Verdacht auf Prostatakarzinom We hypothesize that the image guided biopsy using multiparametric metabolic hybrid imaging with [18F]Fluoroethylcholine (FEC)/[68]Ga-PSMA-PET/MRI is superior in the detection of primary localized pros...

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Prevention of venous thrombosis in cancer patients: A prospective, randomized, double-blind study comparing two different dosages of low-molecular weight heparin to investigate the effect of LMWH on hemostatic system activation, as measured by the levels of F1+2 and D-dimer, in cancer patients to compare the effects of two different dosages of enoxaparin (40 ...

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Effect of furosemid versus placebo on quality of life in hypertensive patients with pulmonary edema Not provided at time of registration

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The Serotonin Transporter's Role in Ketamine's Antidepressant Effects. Die Rolle des Serotonintransporters bei der antidepressiven Wirkung von Ketamin The study at hand is the first to investigate ketamine’s serotonin transporter (SERT) binding in humans, by utilizing the highly selective SERT radioligand [11C]DASB and positron emission tomography (...

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Prospective Randomized Clinical Trial of Total Thyroidectomy (Tx) versus Anti-Thyroid Drugs (ATD) in Patients with Moderate-to-Severe Graves’ Ophthalmopathy - a 1-year Follow-up To examine the difference in the outcome of GO in patients with moderate-to-severe GO, who receive Tx versus further ATD after suffering their first relapse following the initial decrease in ATD after...

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Characterization of myeloma bone lesions - before and during anti-cancer therapy - using 18F-FDG-, 18F-fluoride PET/CT and MRI- a pilot study The primary aim of this study is the characterization of WB MRI detected untreated MM bone lesions in consideration of the mineralization status and tumor activity using 18F-fluorid-PET/CT and 18F FDG...

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