Study of the effects of blocking the enzyme PCSK9 on artery wall inflamation

Update Il y a 5 ans
Reference: EUCTR2015-003731-35

Woman and Man

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Extract

To evaluate the effect of evolocumab on arterial wall inflammation, as measured by percent change from baseline in target-to-background ratio of an index vessel by FDG-PET/CT at week 16 in subjects with baseline lipoprotein (a) [Lp(a)] ≥ 50 mg/dL and low density lipoprotein-cholesterol (LDL-C) ≥ 100 mg/dL


Inclusion criteria

  • Hypercholesterolemia

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