A Phase III Study to Assess the Tolerability and Efficacy of MK-0822 (Odanacatib) in Reducing the Risk of Bone Metastases and Prolonging Disease-Free Survival in Women with Breast Cancer

Update Il y a 5 ans
Reference: EUCTR2008-002119-42

Woman Man

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Extract

Objective: To assess the effect of treatment with MK-0822 5 mg once daily on the risk of developing a first bone metastasis (first disease recurrence) compared to placebo Objective: To assess the effect of treatment with MK-0822 5 mg once daily on disease-free survival compared to placebo Objective: To assess the effect of treatment with MK-0822 5 mg once daily in a subset of 250 patients on lumbar spine, total hip, femoral neck, trochanter and total body bone mineral density (BMD) compared to placebo Objective: To assess the tolerability of treatment with MK-0822 5 mg once daily compared to placebo


Inclusion criteria

  • Prevention of disease recurrence in patients with breast cancer

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