Woman and Man
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Extract
To assess the efficacy of a 6-month daily application of 0.1% , 0.5% and 1% tazarotene fingernail lacquer in fingernail psoriasis, using Expert Physician Global Assessment (EPGA) corresponding to a blinded assessment of photographs using a 6-point scale.
Inclusion criteria
- Psoriasis of the skin is frequently accompanied by nail changes: between 10 and 78% of psoriatic patients suffer from changes of the nails. More than 50% of patients with nail psoriasis have pain because of nail changes, and nearly 60% experience limitations in daily activities. Conventional therapies (e.g., topical agents, triamcinolone acetonide injections, cyclosporine, methotrexate, retinoids, and phototherapy) have limited efficacy, and many have tolerability concerns