High-Dose Corticosteroids for Immune Reconstitution Inflammatory Syndrome in Patients Who Develop Progressive Multifocal Leukoencephalopathy on Natalizumab

Update Il y a 5 ans
Reference: EUCTR2010-020369-26

Woman and Man

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Extract

• To explore the effects of administering high-dose corticosteroids to subjects who develop Progressive Multifocal Leukoencephalopathywhile on natalizumab • To characterize the evolution of Immune Reconstitution Inflammatory Syndrome • To characterize the time course elimination of serum natalizumab concentrations in the study population following the last plasma exchange procedure


Inclusion criteria

  • Immune Reconstitution Inflammatory Syndrome

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