Phase I study of LDK378 in pediatric malignancies with a genetic alteration in ALK

Update Il y a 4 ans
Reference: EUCTR2012-002074-31

Woman and Man

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Extract

Estimate the MTD and/or RDE of LDK378 as a single agent when administered orally to pediatric patients with ALK-activated tumors in the fasted and fed state


Inclusion criteria

  • malignancies characterized by genetic abnormalities in anaplastic lymphoma kinase (ALK)