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An open-label, multicenter study to evaluate the efficacy and safety of a 4 week therapy with the aliskiren 300 mg plus hydrochlorothiazide 25 mg in hypertensive patients not adequately responding to ...

Update Il y a 4 ans
Reference: EUCTR2008-005810-39

An open-label, multicenter study to evaluate the efficacy and safety of a 4 week therapy with the aliskiren 300 mg plus hydrochlorothiazide 25 mg in hypertensive patients not adequately responding to a 4 week therapy with candesartan 32 mg plus hydrochlorothiazide 25 mg

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Extract

To demonstrate that 4 weeks of treatment with aliskiren 300mg plus hydrochlorothiazide 25mg in combination provide an additional mean sitting diastolic blood pressure reduction in hypertensive patients not adequately responding (i.e., MSDBP > 90 mmHg) to 4 weeks of treatment with an agiontensin receptor blocker plus hydrochlorothiazide 25mg in combination (candesartan 32mg plus HCTZ 25mg)

Inclusion criteria

  • Hypertensive patients not adequately responding to a 4 week therapy with candesartan 32 mg plus hydrochlorothiazide 25 mg

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