Kusajili – Clinical trials directory

Pharmacokinetics of a single bolus of dexmedetomidine in ICU patients on continuous veno-venous haemodiafiltration Tutkimuksen tarkoitus on selvittää dexmedetomidiiniboluksen farmakokinetiikka jatkuvan hemodiafiltraation aikana.

• Country None
• organs None
• Specialty None

The characterisation and correlation of cardiovascular haemodynamics and endothelial function in preeclampsia

• Country None
• organs None
• Specialty None

Intra-operatieve fluorescente beeldvorming van schildwachtklieren bij huidkankerpatienten

• Country None
• organs None
• Specialty None

Comparative Study of Radiotherapy Treatments to Treat High Risk Prostate Cancer Patients In North America, the number of new cases of prostate cancer increases every year. Many efforts have been made to develop more efficient and safer curative treatments for high risk prostate cancer patients. This phase III clinical trial is designed to compare the safety of a standard pelvic external beam radiation therapy (EBRT) combined with a high dose rate brachytherapy (HDRB) boost (direct insertion of radiation source over a period of minutes via flexible needles temporarily inserted in the prostate) to a shorter course of hypofractionated dose escalation radiotherapy (larger radiation dose per daily treatment) in patients with high risk prostate cancer. The investigators plan to recruit 296 patients across Quebec who will be randomized in either treatment plan.

• Country None
• organs None
• Specialty None

A Single-blind Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Hantaan Virus DNA Vaccine This is a single-center, randomized, single-blinded study of the HTNV DNA vaccine alone, PUUV DNA vaccine alone, and mixed HTNV/PUUV DNA vaccines delivered IM by the needle-free PharmaJet Stratis DSJI device.

• Country None
• organs None
• Specialty None

A phase III trial of S-1 vs. observation in patients with resected biliary tract cancer ASCOT : Adjuvant S-1 for CholangiOcarcinoma Trial (JCOG1202, ASCOT)

• Country Japan,
• organs None
• Specialty None

Evaluation of the Physiopathological Phenomena and the Haemodynamic and Cerebral Metabolic Effects From Semi-seated Position to Lying Position in Patients With Brain Trauma Brain trauma is an important burden in traumatologic intensive care. In these patients the treatment is guided by a cluster of multimodal monitoring parameters. Despite this it is difficult to assess the actual physiopathologic status of the brain. Changing the position of these patients (semi-seated to lying position) causes changes in the hémodynamics brain conditions, so in monitoring parameters . The analysis of these changes can givr us valuable clinically informations.

• Country None
• organs None
• Specialty None

Effects of Exercise Training on Cognitive Function and Neurotrophic Factors in Overweight Adults The BrainFit Study aims to examine acute effects of High Intensity Interval- vs Resistance or Combined program has benefits on Cognitive Function as well as on secretion and regulation of neurotrophic factors or neurotrophins in a cohort of sedentary, overweight adults (aged 18-30 years) from Bogota, Colombia.

• Country None
• organs None
• Specialty None

Efficacy Study of Olaparib With Paclitaxel Versus Paclitaxel in Gastric Cancer Patients To assess the efficacy of olaparib when given in combination with paclitaxel compared with paclitaxel alone as defined by progression-free survival (PFS), in all patients with recurrent and metastatic gastric cancer who progress following first-line therapy

• Country None
• organs None
• Specialty None

Phenotypes of Adults with Non-Atopic Asthma

• Country The Netherlands,
• organs None
• Specialty None