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Kusajili – Clinical trials directory
Result
of your search per sponsor: Goethe University Frankfurt
Woman and Man Max 99 years
Goethe University Frankfurt
Update Il y a 4 ans
Repeated application of bone marrow-derived stem cells to treat chronic post-infarction heart failure
Improve mortality in patients with symptomatic chronic post-infarction heart failure under full dose conventional medical and device treatment including resynchronization therapy frequently by intraco...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Goethe University Frankfurt
Update Il y a 4 ans
A prospective phase I/II study to investigate the feasibility, safety and efficacy of IL-15 activated cytokine induced killer (CIK) cells in relapsing patients with acute leukemia or myelodysplastic syndromes after allogeneic stem cell transplantation
To assess the safety and feasibility of increasing cell doses of CIK cell transfusions in adult and pediatric leukemia and MDS patients with molecular, cytogenetic or hematologic relapse after allogen...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Decan of Medical Faculty of Goethe University Frankfurt
Update Il y a 4 ans
A multi-centre study to evaluate the drug level of two different HIV drugs in the plasma of children and adolescents and to compare these results to the therapeutic outcome taking the viral resistance profile into account. Eine multizentrische Studie, in der die Plasmaspiegel zweier HIV-Medikamente bestimmt werden sollen und evaluiert werden soll, in wieweit die Plasmaspiegel den Therapieverlauf unter Berücksichtigung der viralen Medikamentenresistenz beeinflussen
Primary endpoint is the number of children with virological failure during the study, wherein failure is defined as either two consecutive viral loads >1000 copies/ml or absence of reduction of viral ...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man
Between 18 years
and 99 years
Goethe University Frankfurt
Update Il y a 4 ans
Étude SUNNIFORECAST : étude de phase 2 randomisée évaluant l’efficacité du nivolumab associé à l’ipilimumab chez des patients ayant un carcinome à cellules rénales à cellules non claires non traité précédemment et de stade avancé.
Un cancer apparaît lorsqu’une cellule du rein initialement normale se transforme, puis se multiplie de façon incontrôlée en formant un amas de cellules anormales qu’on appelle une tumeur cancéreuse. ...
Country
France
organs
Rein
Specialty
Immunothérapie - Vaccinothérapie
Essai ouvert aux inclusions
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Woman and Man Max 99 years
Cardiology, J. W. Goethe University Frankfurt
Update Il y a 4 ans
Doppel-blinde, randomisierte, kontrollierte Studie zur Erfassung des Effektes einer intrakoronaren Applikation von Knochenmark-Progenitorzellen auf die koronare Flußreserve bei Patienten mit akutem Koronarsyndrom (Reinfusion of Enriched Progenitor Cells And Infarct Remodeling in Acute Coronary Syndrome; REPAIR - ACS)
Myocardial infarction leads to microvascular dysfunction with consecutively reduced coronary flow reserve, which persists after 4 months. Moreover, recent clinical trials have shown that a reduced cor...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Dean of Medical Faculty of Goethe University Frankfurt
Update Il y a 4 ans
A study with Kaletra to compare concentration levels in the human body of Kaletra-softgel capsules or –suspension to Kaletra-tablets in pediatric patients – C2T
Comparison of pharmakokinetic parameters of the different formulations (tablets, capules and oral solution)
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Goethe University Frankfurt
Update Il y a 4 ans
A Phase 2, Randomized, Open-Label Study of Nivolumab Combined with Ipilimumab Versus Sunitinib Monotherapy in Subjects with Previously Untreated and Advanced (unresectable or metastatic) non-clear Cell Renal Cell Carcinoma
The primary objective of the study is to compare the of OS rate at 12 months of Nivolumab combined with Ipilimumab to Sunitinib monotherapy in patients with previously untreated and advanced non-clear...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Goethe University Frankfurt
Update Il y a 4 ans
Optimization of therapy in adult patients with newly diagnosed acute lymphoblastic leukemia or lymphoblastic lymphoma by individualised, targeted and intensified treatment
To improve event free survival (EFS), remission duration (RD), disease free survival (DFS) and overall survival (OS) compared with the previous trial GMALL 07/2003
Country
None
organs
None
Specialty
None
unknown
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