A 2-year randomized, multicenter, double-blind, placebocontrolled study to determine the efficacy and safety of intravenous zoledronic acid 5 mg administered either annually at randomization and 12 months, or administered at randomization only in the prevention of bone loss in postmenopausal women with osteopenia - To demonstrate that zoledronic acid 5 mg i.v. given annually at randomization and Month 12 is superior to placebo in percent change of BMD at the lumbar spine at Month 24 relative to baseline in Str...

• Country None
• organs None
• Specialty None

IBS-C Study A2306 Not provided at time of registration

• Country United States
• organs None
• Specialty None

A study of the Palatability and Tolerability of Exjade Taken with Meals, with Different Liquids or Crushed and Added to Food To evaluate the palatability of Exjade administered with meals, added to different liquids and crushed and added to food

• Country None
• organs None
• Specialty None

A study to compare two different forms of the same medicine (deferasirox tablet that is dissolved in liquid form vs. deferasirox film-coated tablet form) to see how much of each type of medicine ends up in the blood Evaluate the PK comparability of deferasirox with a reduced dosage strenght of the Film-coated tablet(FCT) vs. the dispersible tablets (DT) in healthy subjects under fasted conditions.

• Country None
• organs None
• Specialty None

A double-blind, randomized, multi-center active-controlled, parallel-group study comparing the combination of valsartan 320 mg plus hydrochlorothiazide 12.5 mg and valsartan 320 mg plus hydrochlorothiazide 25 mg to valsartan 320 mg in mild to moderate hypertensive patients not adequately controlled with valsartan 320 mg To demonstrate the blood pressure reduction effect of valsartan/HCTZ 320/25 mg o.d. or 320/12.5 mg o.d. in patients with mild to moderate hypertension not adequately controlled with valsartan 320 mg ...

• Country None
• organs None
• Specialty None

Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients To assess the safety of ICL670 compared to deferoxamine during 24 weeks in patients with sickle cell disease and iron overload from repeated blood transfusion.

• Country None
• organs None
• Specialty None

A study comparing Tobramycin Inhalation Powder (TIP) administered once daily continuously versus TIP administered BID in 28 day on / 28 day off cycles for the treatment of pulmonary Pseudomonas aeruginosa in patients with cystic fibrosis To provide efficacy and safety data comparing two dosing schedules of Tobramycin Inhalation Powder (TIP) for the treatment of pulmonary Pseudomonas aeruginosa in patients with cystic fibrosis.

• Country None
• organs None
• Specialty None

A study to compare two different forms of the same medicine (deferasirox tablet that is dissolved in liquid form vs. deferasirox granule form) to see how much of each type of medicine ends up in the blood Evaluate the PK comparability of a reduced dose of the deferasirox granule formulation given with a small amount of a soft food matrix (apple sauce) versus the reference dispersible tablet formulation...

• Country None
• organs None
• Specialty None

Study to Validate the Instructions for Use of TOBI® Podhaler™ in Cystic Fibrosis Patients To determine whether CF patients, representative of potential TOBI® Podhaler™ users, could understand and follow the approved IFU and the extent to which the approved IFU supports safe and effective u...

• Country None
• organs None
• Specialty None