A trial to investigate the role of the food supplement inositol in the general health of those at risk of developing gestational diabetes mellitus Background and study aims Gestational diabetes mellitus is a form of diabetes that can occur in pregnancy. This can affect both mother and baby during the course of the pregnancy and delivery. Inosito...

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Ultrasound assessment of the fetal head position to prevent morbidity at instrumental delivery Not provided at time of registration

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Can High Flow Nasal Prongs therapy facilitate earlier establishment of full oral feeds in babies who are Nasal Continuous Positive Airway Pressure dependent at 32 weeks gestation? Background and study aims Respiratory Distress Syndrome (RDS) is a common condition in preterm infants. NCPAP (Nasal Continuous Positive Airway Pressure) is a method of ventilatory support used for th...

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Stopping smoking to optimise pregnancy Background and study aims About 13% of women having babies in the Coombe Hospital smoke cigarettes. This is associated with an increased risk of having a baby weighing less than 2.5kg at birth, and of...

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The POPS trial (PICC Out Parenteral nutrition Stopped): In preterm infants less than 1500grams, does stopping intravenous nutrition and removing Peripherally Inserted Central Venous Catheters (PICC lines) at 100mls/kg/day of oral feeds compared to 140mls/kg/day (full oral feeds) significantly increase time to regain birth-weight? Background and study aims Very low birth weight infants (infants less than 1500grams) can initially only tolerate small amounts of oral feeds due to their immature digestive systems. Feeds (breast mil...

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The use of Low Flow Nasal Prongs Therapy in weaning nasal Continuous Positive Airway Pressure (nCPAP) in neonates. Anecdotal or Evidence Based? Not provided at time of registration

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