A Phase 1b/2 study of AMG 655 Combination with Paclitaxel and Carboplatin for the First-Line Treatment of Advanced Non-Small Cell Lung Cancer

Mise à jour : Il y a 4 ans
Référence : EUCTR2006-006658-89

Femme et Homme

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Extrait

Part 1 (Phase 1b): To determine the maximum tolerated dose up to a target dose of 15 mg/kg of AMG 655 that can be administered in combination with paclitaxel/carboplatin Part 2 (Phase 2): To estimate the efficacy of AMG 655 as assessed by progression free survival time (at two doses selected in part 1) in combination with paclitaxel/carboplatin


Critère d'inclusion

  • Stage IIIb/IV Non-Small Cell Lung Cancer