Extrait

Background and study aims Dry eye disease occurs when the eyes do not make enough tears or the tears evaporate too quickly, leading to the eyes drying out and becoming inflamed (red and swollen) and irritated. Our aim is to study the effect of daily topical administration of a drug called a TRPM8 agonist in patients with mild to moderate dry eye disease. Who can participate? Patients with mild to moderate dry eye. What does the study involve? Patients are randomly allocated to be treated with either TRPM8 agonist dissolved in distilled water, or distilled water only. Study medications will be topically applied to the upper eyelid 4 times daily (every 6 hours) for 2 weeks with using a stick filled with TRPM8 agonist or distilled water only. What are the possible benefits and risks of participating? The treatment may relieve dry eye related eye symptoms. There are no risks involved in this study. Where is the study run from? Department of Ophthalmology, Chonnam National University Medical School and Hospital (South Korea). When is the study starting and how long is it expected to run for? From January 2015 to August 2015. Who is funding the study? Investigator initiated and funded (South Korea). Who is the main contact? Pf. Kyung Chul Yoon [email protected]

Critère d'inclusion

• dry eye

Liens

• ictrp
• isrctn